Great Horned Owls (Bubo virginianus) are the only predators that kill and eat skunks.
They will eat American Crows, both adults and young, nestling Ospreys, and even other owls.
Information from The Young Birder’s Guide to Birds of Eastern North America and the Cornell Lab of Ornithology
Wow, I didn’t know that. Cool fact indeed!! 🙂
Very neat. Owls are so awesome!